Clinical Usefulness of Soluble Fms-like Tyrosine Kinase 1, Soluble Endoglin and Placental Growth Factor in Korean Women with Preeclampsia
نویسندگان
چکیده
Results The mean serum level of sFlt-1 and sEng in women with preeclampsia was significantly higher than normal pregnancy. But the mean serum level of PIGF had no signifi cant difference between two groups. The cut-off values of sFlt-1 and sEng showing differential signifi cance were 26.3 ng/mL and 21.1 ng/mL each. Then the sensitivity, specifi city, positive predictive value, negative predictive value was all over 80%. Serum levels of sFlt-1 and sEng were not signifi cantly different between intrauterine growth restriction (IUGR) and non-IUGR group among preeclamptic women.
منابع مشابه
Angiogenic factors in superimposed preeclampsia: a longitudinal study of women with chronic hypertension during pregnancy.
Imbalances in circulating angiogenic factors contribute to the pathogenesis of preeclampsia. To characterize levels of angiogenic factors in pregnant women with chronic hypertension, we prospectively followed 109 women and measured soluble fms-like tyrosine kinase 1 (sFlt1), soluble endoglin, and placental growth factor at 12, 20, 28, and 36 weeks' gestation and postpartum. Superimposed preecla...
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